Tishler, Max

Led mass production of penicillin in WW II and developed large-scale postwar vaccines and drugs

Price: $30.00

Description:
(1906-1989) Ph. D. chemist, senior vice president of research and development then President of Merck, Sharp and Dome Research Laboratories to 1970. At Merck, he developed commercial production of vitamin B12, as well as vitamins C, B6, D, E, and K1. He was coauthor of the first synthesis of hydrocortisone and the first isolation of actinomycin D, used in the treatment of Wilms tumors. Through his efforts, Merck mass-produced penicillin in World War II. Under his leadership, Merck developed vaccines against measles, mumps, German measles, as well as drugs for heart disease, hypertension, rheumatoid arthritis, and clinical depression and products for the control of poultry and livestock diseases. His creation of a process for large scale manufacturing of cortisone is considered by many to have revolutionized the pharmaceutical industry. Dr. Tishler received the National Medal of Science in 1987. He is listed on approx. 100 US patents at Merck. TLS, 2pp (separate leaves) on 11 x 8 ½ letterhead as President of Merck Sharp & Dohme Research Laboratories, Division of Merck & Co., Rahway, New Jersey, December 13 1967, to Associate Editor, Chemical & Engineering News. Responding to a request for comment on the “controversy surrounding the INDOCIN study by Dr. Mainland”, he clarifies Merck’s position on the Mainland Study and makes two points on the significance of concomitant aspirin usage. He concludes that "...aspirin is as effective as the other medications in patients demonstrably responsive to salicylates." Interesting scientific detail, looks forward “...enthusiastically to your comprehensive article on the arthritic diseases.”

Condition: Very good, staple holes top left, docket stamp top right, 2 stray pencil notations
Type:Letter






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